Sex and Sex Hormone–Dependent Cardiovascular Stress Responses

Sex differences in stress responses: social rejection versus achievement stress.

BACKGROUND Sex differences in stress responses may be one mechanism underlying gender differences in depression. We hypothesized that men and women would show different adrenocortical responses to different stressors. In particular, we predicted that women would show greater responses to social rejection stressors, whereas men would demonstrate greater responses to achievement stressors. METH...

Aged rats: sex differences and responses to chronic stress.

Cognitive, as well as physiological, sex differences exist in young adult rats under both basal conditions and following chronic stress; however, few studies have examined whether sex differences remain in aged subjects and whether responses to stress are altered. We compared aged male and female Fischer 344 rats (21.5 months at testing) without stress and when given 21 days of restraint for 6 ...

Sex differences in chronic stress responses and Alzheimer's disease

Stress, sex and evolution

genetics and you are bound to find phrases such as ‘stress reveals genetic variation’. The implication is that while many stresses have a slight effect on an ‘average’ organism, if the organism has a mutation then the stress can have greater impact. For bacteria this would be revealed in reduced growth. At the very least you would expect growth of mutated organisms to be inhibited by stress to ...

Sex steroids and cardiovascular disease

As men grow older, testosterone (T) levels decline and the significance of this change is debated. The evidence supporting a causal role for lower circulating T, or its metabolites dihydrotestosterone (DHT) and estradiol, in the genesis of atherosclerosis and cardiovascular disease (CVD) in men is limited. Observational studies associate low baseline T levels with carotid atherosclerosis, aorti...